Search results for "non-ribosomal peptides"

showing 3 items of 3 documents

The LuxR Regulators PcoR and RfiA Co-regulate Antimicrobial Peptide and Alginate Production in Pseudomonas corrugata

2018

Cyclic lipopeptides (CLPs) are considered as some of the most important secondary metabolites in different plant-associated bacteria, thanks to their antimicrobial, cytotoxic, and surfactant properties. In this study, our aim was to investigate the role of the Quorum Sensing (QS) system, PcoI/PcoR, and the LuxR-type transcriptional regulator RfiA in CLP production in the phytopatogenic bacterium, Pseudomonas corrugata based on our previous work where we reported that the pcoR and rfiA mutants were devoid of the CLPs cormycin and corpeptin production. Due to the close genetic link between the QS system and the RfiA (rfiA is co-transcribed with pcoI), it was difficult to ascertain the specifi…

0301 basic medicineMicrobiology (medical)transcriptional analysiscyclic lipopeptides RNA-seq non-ribosomal peptides transcriptional analysis exopolysaccarides030106 microbiologyAntimicrobial peptidesMutantexopolysaccarideslcsh:QR1-502exopolysaccarideMicrobiologylcsh:Microbiology03 medical and health sciencescyclic lipopeptideGene expressionnon-ribosomal peptideTranscriptional regulationGenebiologyChemistrySettore AGR/12 - Patologia Vegetalebiology.organism_classificationQuorum sensingPseudomonas corrugatacyclic lipopeptidesRegulonBiochemistrynon-ribosomal peptidesRNA-seqFrontiers in Microbiology
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Cyanobacteria and their metabolites in mono- and polidominant shallow eutrophic temperate lakes

2022

Monodominant (one species dominates) or polidominant (multiple species dominate) cyanobacterial blooms are pronounced in productive freshwater ecosystems and pose a potential threat to the biota due to the synthesis of toxins. Seasonal changes in cyanobacteria species and cyanometabolites composition were studied in two shallow temperate eutrophic lakes. Data on cyanobacteria biomass and diversity of dominant species in the lakes were combined with chemical and molecular analyses of fifteen potentially toxin-producing cyanobacteria species (248 isolates from the lakes). Anatoxin-a, saxitoxin, microcystins and other non-ribosomal peptides formed the diverse profiles in monodominant (Planktot…

MicrocystistoksiinitrehevöityminenHealth Toxicology and MutagenesisPublic Health Environmental and Occupational HealthAphanizomenon gracilemicrocystinssaxitoxinCyanobacteriavedenlaatuBiotajärvetLakespeptiditanatoxin-anon-ribosomal peptidesBiomassanatoksiini-asyanobakteeritmicrocystins; saxitoxin; anatoxin-a; non-ribosomal peptides; oligopeptides; <i>Aphanizomenon gracile</i>; <i>Microcystis</i>; <i>Planktothrix agardhii</i>oligopeptidesPlanktothrix agardhiiEcosystem
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The LuxR Regulators PcoR and RfiA Co-regulate Antimicrobial Peptide and Alginate Production in

2017

Cyclic lipopeptides (CLPs) are considered as some of the most important secondary metabolites in different plant-associated bacteria, thanks to their antimicrobial, cytotoxic, and surfactant properties. In this study, our aim was to investigate the role of the Quorum Sensing (QS) system, PcoI/PcoR, and the LuxR-type transcriptional regulator RfiA in CLP production in the phytopatogenic bacterium, Pseudomonas corrugata based on our previous work where we reported that the pcoR and rfiA mutants were devoid of the CLPs cormycin and corpeptin production. Due to the close genetic link between the QS system and the RfiA (rfiA is co-transcribed with pcoI), it was difficult to ascertain the specifi…

transcriptional analysiscyclic lipopeptidesexopolysaccaridesnon-ribosomal peptidesRNA-seqMicrobiologyOriginal ResearchFrontiers in microbiology
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